Exon 2 was flanked by loxP sites and neo cassette with a 3' lox P site was inserted downstream of exon 2. This exon encodes the entire mature domain of the protein and a conditional deletion of exon 2 would result in a null allele. (J:125354)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count