A genomic construct containing a 4.7 kb Xbal-Xbal fragment, which includes the entire mouse apoC-III gene plus 2 kb of 5' and 1 kb of 3' sequence, was used for the transgene. Northern blot and densitometry analysis showed that Apoc3 mRNA was increased 4-fold in liver and 5-fold in the intestine. (J:34875)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x CBA
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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