Tg(Apoc3)5381Bres

A genomic construct containing a 4.7 kb Xbal-Xbal fragment, which includes the entire mouse apoC-III gene plus 2 kb of 5' and 1 kb of 3' sequence, was used for the transgene. Northern blot and densitometry analysis showed that Apoc3 mRNA was increased 4-fold in liver and 5-fold in the intestine. (J:34875)