The central portion of the DFL16.1 segment was replaced with the inverted coding sequence of the DSP2.2 segment and a downstream loxP neo cassette. This vector was used in targeting ES cells from Ightm1.1Lnit that had the DQ52 segment replaced with a loxP site. (J:124421)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count