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ES cell containing Fosl2tm2Wag were transfected with a cre-expressing plasmid to remove the exons 3 and 4 along with a neo cassette. RNase protection and western blot were used to confirm the absence of full-length protein from mouse embryonic fibroblasts using an anti-Fosl2 antibody. However, a fusion protein with the remaining GFP open reading frame is detected using an anti-GFP antibody. (J:125028)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
