The exons encoding the signal peptide and Ig domains were replaced with a GAL4 and neo cassette. Correct insertion was confirmed by Southern blot. Absence of mRNA expression was confirmed in all tissues examined including spleen, lymph node, thymus and kidney. (J:125054)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count