Log In|Sign Up
EN
An IRESLacZ reporter and a neo selection cassette replaced a 1051 bp genomic fragment including all but the first 92 bp of exon 1. Quantitative RT-PCR indicated that heterozygote mice expressed about half the level of mRNA as wild-type mice, with no mRNA being detected in homozygote mice. LacZ expression was detected in the stomach, intestines, pancreas and brain of homozygote mice. (J:124913)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
