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The three coding exons downstream of the translation initiation site was replaced with Cre recombinase cDNA. The remaining gene will lack critical amino acids including the codon that encodes the essential catalytic triad residue His75. Absence of wild type protein was confirmed by immunoblot. (J:124554)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
