LoxP sites were inserted to flank the first two coding exons of the locus. An frt-flanked neo was included in the vector and subsequently removed by crossing with FLP deleter mice. (J:124329)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count