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A targeting construct removed exon 9 and placed a floxed neo cassette into the upstream intron. Chimeric mice were bred with Cre transgenic mice to excise the neo cassette. No protein was expressed in homozygous mice as measured by western blots of heart tissue. (J:124211)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
