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An extra copy of exon 4, interrupted by the lacZ coding sequence with a polyadenylation signal, has been inserted in reverse orientation upstream of the endogenous exon 4. A loxP-flanked neomycin resistance cassette (neo), in normal orientation, resides upstream of the reversed exon4-lacZ, separated from the latter by a V(D)J recombination signal sequence (RSS) with a 12-bp spacer. An RSS with a 23-bp spacer lies downstream of the endogenous exon 4. (J:124224)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
