A targeting vector was designed to mutate Thr51 and Thr53 into alanines in exon 4 (T51A, T53A). A floxed neo was inserted into intron 3. (J:123909)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count