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Human MAPT cDNA encoding the longest tau isoform of 441 amino acids (called tau40) containing four repeats, with 2 N-terminal inserts was inserted into a murine Thy1 expression vector. Founder line 1 was established by breeding with FVB/N females. Expression of human tau (MAPT) protein exclusively in brain and spinal cord was detected by Western blotting. (J:100972)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
