The pGT1Lxf gene trap vector containing a beta-geo inserted into intron 10. A 5.1 kb transcript was detected with the expected size of the fusion between the truncated locus (exons 1-10) and the beta-geo. Because the transcript was disrupted before the highly conserved PUMILIO homology domain, a functional protein is unlikely. (J:123531)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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