A green-fluorescent protein was inserted into the first exon of the gene to generate a null allele. A floxed neo cassette inserted downstream of the modified exon 1 was removed by cre-mediated recombination. (J:123547)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count