LoxP sites were inserted to flank the promoter region and exon 1 of transforming growth factor, beta 1 as well as B9 protein domain 2. A floxed neo included in the vector was removed via transient cre expression. (J:123547)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count