A targeting vector was designed to insert loxP sites flanking exon 4. Downstream of the floxed exon, an frt-flanked sequence containing a stop cassette-IRES-GFP-neo was inserted into the locus. (J:104408)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count