The gene trap vector inserted between exons 22 and 23, disrupting the second RNase III domain and resulting in the loss of the double-stranded RNA binding domain. Slight detection of the transcript was detected, indicating leaky expression of the locus caused by an imperfect trap. (J:108137, J:123635)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count