The C1 mutation was introduced into exon 7 of the locus. This mutation contains the K233Q, K235Q, and R236Q substitutions. A floxed neo was inserted into intron 6 and subsequently removed via cre mediated recombination. (J:123299)
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The C1 mutation was introduced into exon 7 of the locus. This mutation contains the K233Q, K235Q, and R236Q substitutions. A floxed neo was inserted into intron 6 and subsequently removed via cre mediated recombination. (J:123299)