Log In|Sign Up
EN
This transgene was designed to express cre recombinase during pituitary developmental stages starting at e13.5, using a 15.5 kb POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) promoter. An IRES separated the cre cDNA from the human placenta alkaline phosphatase gene and polyA signal. The promoter is capable of driving expression in all three cell lineages: the somatotrophs, lactotrophs and thyrotrophs. (J:123618)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
