The transgenic construct contained full length murine Tert cDNA adjoined to the bovine KRT5 regulatory region, active in basal keratinocytes. Upregulation of telomerase activity was observed in stratified epithelia of uterus, trachea, and skin tissue obtained from transgenic mice. (J:69757)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x DBA/2
--
Insertion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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