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A 14.5 kb fragment of human genomic DNA containing the entire SOD1 gene, including its regulatory sequences, was used for microinjection into fertilized eggs. Line 51 contains 4-5 copies of the transgene and expresses 3-5-fold more superoxide dismutase 1in the brain than non-transgenic mice. (J:96742)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
