LoxP sites were inserted in the introns flanking the second coding exon. The neomycin resistance cassette was removed by breeding with mice expressing FLPe recombinase in the germline. (J:119152)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count