Log In|Sign Up
EN
The cDNA encoding the three-repeat human fetal tau (MAPT) protein (shortest human isoform) without the N-terminal insert was inserted after the mouse Hmgcr promoter region, exon 1 (not translated) and major intron 1, in the pHMG vector. The construct was microinjected into (C57BL/6J x CBA)F2 fertilized embryos. Line 23 was established. Human tau (MAPT) protein is detected in cell bodies and dendrites of neurons in many brain areas in adult animals with Western blots. (J:101993)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
