The protein-coding region of the human Kruppel-like factor gene KLF4 was ligated to a vector fragment containing a tetracycline-responsive element and the minimal human cytomegalovirus promoter to produce the transgene construct. The 4.4 kb fragment was injected into (C57BL/6 x SJL)F2 ova. (J:96886)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count