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The GFP open reading frame was inserted into exon 1 beginning at the initiator ATG of the Scx gene and replacing most of the first exon. The transgene construct retains the splice donor sequences of exon 1 such that the transcripts of the transgene are spliced to include exon 2. The construct was injected into fertilized eggs and 2 lines were generated that showed robust expression in tendons and tendon progenitors. One line was found to be homozygous viable and was propagated for detailed analysis. (J:121561)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
