The transgene construct consisted of a bidirectional tet-responsive element, a CMV minimal promoter, and a human LEFTY2 cDNA clone. After two weeks of administration of Dox, the lefty gene expression was inducible in epithelial-lined organs including liver, uterus, kidney, etc. (J:94077, J:123054)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count