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This transgene expresses the cDNA of the human isoform of protein tyrosine phosphatase 1B (PTPN1) from the mouse muscle creatine kinase promoter. Transgenic mice overexpress this construct 1.8 fold in skeletal muscle. No overexpression was detected in heart. (J:122895)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
