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An IRES-lacZ and a neo cassette replaced a 115 bp section of sequence encoding amino acids 74 to 112. Brain expression of lacZ, as revealed by X-gal staining, is heterogeneous, being greatest in the brainstem, midbrain, diencephalon and cerebellum and low in forebrain regions; in the spinal cord, expression is restricted to the gray matter. (J:100127)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
