The Dvl2 promoter drives the expression of Dvl2 with EGFP fused downstream of the 15th exon with a LoxP site inserted 3' to Acadvl. The DIX domains, amino acids 67 to 159, was removed abolishing beta-catenin Wnt signaling. (J:108512)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count