Exon 1 was removed via cre mediated recombination. The floxed neo that was included in the targeting vector remained in the locus. Immunostaining confirmed absence of protein in mutant mice. (J:122519)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count