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A targeting construct was designed to insert a floxed PGK-hygro into intron 24, and a third loxP site into intron 24d. The floxed region encompassed the CCC region and was removed by crossing with mice expressing cre recombinase in the germline. The final result was a chimeric intron composed of the upper half of intron 24 and the lower part of intron 24d. (J:122549)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
