LoxP sites were inserted into introns 4 and 6, flanking sequence that encodes the homeodomain. The construct also contains a loxP-flanked neomycin selection cassette. A Cre expression plasmid was used to remove the floxed neo cassette. (J:122505)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count