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The vector contained a self-splicing floxed ACN cassette containing a neo and a cre recombinase gene and was inserted to replace exons 4-6. The final allele contains a sinlge loxP site in place of the exons as the neo and cre were deleted upon passage through the male germline. RT-PCR confirmed successful recombination of the locus in mutant kidney samples. (J:122325)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
