A targeting vector was designed to insert an IRES-YFP-polyA cassette followed by a loxP-TK(delta)-neo-loxP cassette 55 nucleotides downstream of exon 4 splicing acceptor, thereby eliminating the remainder of the ORF. The floxed neo was subsequently removed by crossing with mice expressing cre recombinase in the germline. (J:122275)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion
--
1
3
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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