Mutant mice carrying the Bmp4tm1Jlch allele were crossed with transgenic mice expressing Cre under the control of the CMV promoter, removing the neomycin resistance cassette in the germ line, leaving the two point mutations in exon 4 and a single loxP site downstream of exon 4. (J:108516)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count