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EN
Insertion of a neomycin resistance cassette introduced two point mutations into exon 4 and placed a neomycin selectable marker flanked by loxP sites downstream of exon 4. The S2G mutation causes a single amino acid change predicted to prevent cleavage of the S2 site of the protein, and a silent point mutation that codes for a PvuI site in place of a BglII site. (J:108516)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
