A 14kb construct containing a functionally rearranged kappa light chain from hybridoma clone 36-71 expressing an antibody to p-azophenylarsonate (Ars) and containing natural intron and 3' enhancers was used. The Vk-Jk exon carries 11 amino acid replacements resulting from natural somatic mutagenesis. (J:122260)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count