A codon optimized version (for mammalian translation) of the reverse tetracycline transactivator was cloned behind the 5.5kb alpha myosin heavy chain promoter. Reporter construct assays showed that this transgene is uniformly transcribed in cardiac myocytes, and not in various other tissues tested. (J:70619)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/NTac
--
Insertion
--
--
--
26

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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