A targeting contruct was designed to insert loxP sites to flank exon 3, containing the PHD motif. Crossing with mice expressing cre recombinase in the germline removed exon 3 from the locus. (J:121918)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count