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The gene trap vector containing a beta-galactosidase/neomycin gene was inserted within intron 18. RT-PCR confirmed that mutants contained a truncated mRNA resulting from the splicing of exon 18 to the beta-geo cassette using the cryptic splice site from the gene trap vector. The resulting protein is predicted to be inactive as it lacks the 129 amino acids of the tail domain. (J:121799)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
