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These mice contain an insertion of the human F137L mutation in the third transmembrane region. A floxed sequence, including the wild-type coding sequence for the third transmembrane region and an frt-flanked neo, was located downstream of the F137L mutation. Crossing these mice with mice expressing Flp recombinase in the germline resulted in the loss of the neo. (J:121802)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
