Exon 1 was flanked by loxP sites. Transient expression of cre recombinase removed the floxed sequence. RT-PCR confirmed absence of transcript in mutant liver. (J:121381)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count