A cre recombinase cDNA was inserted upstream to replace the first 3 codons in exon 1. A floxed neo was removed by Flp recombinase in the germline. (J:121230)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count