Log In|Sign Up
EN
A composite fragment composed of 400bp from exons 1-3 of a BTK cDNA as well as 27kb genomic fragment containing exons 3-19 of BTK was placed under the control of the promoter region of human CD19. A Y223F mutation was introduced into this construct by double stranded site-directed mutagenesis. (J:120989)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
