The Vbeta13 gene segment with its endogenous promoter and recombination signal sequences and a floxed pgk-neomycin resistance cassette is inserted upstream of the D segment. Insertion was confirmed by Southern blot analysis of ES cells and by increased expression of Vbeta13 T cells in homozygous mice. (J:120387)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count