An FRT-flanked neo cassette with a single 3' loxP site was inserted between exons 2 and 3 and an additional loxP site was inserted downstream of exon 6. The neo cassette was subsequently removed through flp mediated recombination. (J:120783)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count