A floxed neo cassette was inserted after exon 2 and a single loxP site was inserted after exon 6. In vivo Cre-mediated recombination then removed the neo cassette and exons 3 through 6 creating a null allele. (J:120783)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count