A targeting construct was designed to remove the 5' portion of exon 5 by replacement with a floxed neomycin resistance gene and subsequent removal by cre recombinase in the germline. (J:120323)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count