Log In|Sign Up
EN
The transgene includes the SV40 large T antigen (Tag) gene, containing a deletion in the early region that eliminates expression of small T antigen, driven by the rat probasin promoter fragment extending from -11500 to +28 bp ("large probasin promoter"). Seven lines were established: 12T-1, 12T-5, 12T-7f, 12T-7s, 12T-8. 12T-10, and 12T-11. This 12T-7f line contains multiple copies of the transgene. (J:48623)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
