The second zinc-finger of the locus, encoded by exon 3, was replaced by exon 4 of the nuclear receptor subfamily 3, group C, member 1, resulting in a chimeric protein. A floxed neo was included in the vector downstream of the exon substitution and was subsequently removed via cre mediated recombination. (J:120102)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
11
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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