The second zinc-finger of the locus, encoded by exon 3, was replaced by exon 4 of the nuclear receptor subfamily 3, group C, member 1, resulting in a chimeric protein. A floxed neo was included in the vector downstream of the exon substitution and was subsequently removed via cre mediated recombination. (J:120102)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count